Rane, RV, Oakeshott, JG, Nguyen, T., Hoffmann, AA, & Lee, SF (2017). Ortho-a new pipeline for predicting high quality orthologous gene sets applicable to complete and draft genomes. BMC genomics , 18 (1), 673.
Genes that descent from the same ancestral sequence separated by a speciation event.
groups of 1:1 orthologues with one gene per species existing in orthogonal relationships.
Multiple orthogroups clustered together based on shared protein domains.
Inparalogues (Gene duplications) :
Gene expansions that may have occured after speciation events.